The Reds are boosted by the return of the Belgian striker and the skipper to the bench as they look to match Sevilla's competition record of four triumphs
Jurgen Klopp has selected the same XI that secured Liverpool’s progress to the Europa League final against Villarreal for Wednesday night’s showpiece against Sevilla.
The manager is, however, boosted by a stronger bench at St Jakob-Park, with captain Jordan Henderson and striker Divock Origi named in reserve.
The England midfielder returned from a knee injury in the 1-1 draw against West Brom in the final Premier League clash of the season on Sunday, where he was afforded half-an-hour of action.
The 21-year-old, meanwhile, is involved for the first time since a nasty tackle from Ramiro Funes Mori in the Merseyside derby damaged his ankle ligaments.
Origi netted in both legs of the 5-4 aggregate win over Borussia Dortmund in the quarter-finals.
Back-up goalkeeper Danny Ward is also fit enough to be named as a substitute after shaking off a minor knee complaint.
This is the first-ever meeting between Liverpool and Sevilla, which sees Alberto Moreno line up against his former club.
Meanwhile for their opponents, Sergio Escuerdo has been brought in as a replacement for French left-back Benoit Tremoulinas in Unai Emery's only change from the team that beat Shakhtar Donetsk in their semi-final second-leg.
Liverpool starting XI: Mignolet; Clyne, Toure, Lovren, Moreno; Milner, Can, Coutinho, Lallana; Firmino; Sturridge
Liverpool subs: Ward, Skrtel, Lucas, Allen, Henderson, Benteke, Origi
Sevilla starting XI : Soria; Mariano, Rami, Carrico, Escudero; N’Zonzi, Krychowiak; Vitolo, Banega, Coke; Gameiro
Sevilla subs: Rico, Kolodziejczak, Iborra, Cristoforo, Pareja, Konoplyanka, Llorente