The 26-year-old Chile star missed Sunday's 5-0 win over Aston Villa
due to a hamstring problem and was originally ruled out of the clash at
Spurs as well.But Sanchez is desperate to prove his fitness in time to make the squad for the trip to White Hart Lane.
Wenger said: "He wants to play, he's so keen.
"[Telling him he’s not playing] is not easy! He wants to play of course. He’s very keen and thinks he can even defy the medical people because he’s so keen.
I don’t know yet [if he could feature], I need medical advice on that and need as well to see what he can do in training."
The rout of Villa at The Emirates saw Theo Walcott mark his first start in over a year with a goal - and Wenger believes that even if Sanchez fails to recover in time, the Gunners will still pose enough of a threat in attack.
The Frenchman added: "We have enough offensive power. We don't need to worry about being short on that front."
Sanchez has struck 18 goals in 32 appearances for Arsenal since arriving from Barcelona in the summer for an undisclosed fee reported to be around £35m